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Fig. 5 | Neural Development

Fig. 5

From: Expression and functional analysis of the Wnt/beta-catenin induced mir-135a-2 locus in embryonic forebrain development

Fig. 5

miR-135b expression in the embryonic forebrain. a-c Xgal staining of E12.5 whole mount (lateral view) (a) and E12.5 coronal sections (b-c), showing expression of lacZ exclusively in the ventral forebrain of mir-135b flox/+ mice harboring a LacZ reporter gene in the mir-135b locus. d RT-qPCR on wild type dorsal and ventral forebrain tissue samples (n = 3). miR-135b fold induction was normalized to microRNA sno202. ***, p value <0.001. LGE, lateral ganglionic eminences; MGE, medial ganglionic eminences; PSB, pallium-subpallium boundary; ncx, neocortex. Scale 200 μm in panels b and c

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Neural Development

ISSN: 1749-8104