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Fig. 6 | Neural Development

Fig. 6

From: Identification of molecular signatures specific for distinct cranial sensory ganglia in the developing chick

Fig. 6

Expression patterns of vestibulo-acoustic ganglion-specific markers. A-F) Wholemount in situ hybridization of vestibulo-acoustic ganglion specific markers at HH21. A’-F”’) Transverse sections at the level of the Tmm ganglion (A’-F’), VA ganglion (A”-F”) and P ganglion (A”’-F”’) stained with the named marker at HH21, showing VA-specific expression. A-A”’) ESRRG; B-B”’) HMX3; C-C”’) IRX2; D-D”’) POU6F2; E-E”’) RUNX1; F-F”’) FGF9. Levels of staining in the vestibulo-acoustic ganglion vary, but are stronger when compared with other ganglia. In ESRRG staining is also seen in nascent neurons migrating from the OV (arrowhead). Staining can be seen in the NT although specific localisation and level varies. The dark staining in the eye and OV in B and E was not observed on sections and likely represents background. Abbreviations: NT: neural tube; OV: otic vesicle; P: petrosal ganglion; Tmm: trigeminal maxillomandibular lobe; VA: vestibulo-acoustic ganglion; arrowhead: nascent neurons migrating from OV. Scalebars: A-I: 500 μm; A’-I”’: 150 μm

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