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Fig. 5 | Neural Development

Fig. 5

From: Deltex1 is inhibited by the Notch–Hairy/E(Spl) signaling pathway and induces neuronal and glial differentiation

Fig. 5

Disruption of Dtx1 expression by using dtx1 ΔIII or dtx1 morpholino reduces neuronal differentiation. a The injection of dtx1 ΔIII or dtx1 morpholino caused an identical phenotype, which downregulated neurog1 (a) and HuC/D expression (b) The phenotypes caused by the morpholino injection could be rescued by a concomitant injection of dtx1 full cRNA. The embryo stages are shown in the bottom left corner of each panel. c qPCR analysis confirmed the results obtained through in situ hybridization in a d Counting the HuC/D-positive cells confirmed the results obtained in b *, P < 0.05; **, P < 0.01; ***, P < 0.001

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Neural Development

ISSN: 1749-8104