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Fig. 5 | Neural Development

Fig. 5

From: Ephrin-A2 and ephrin-A5 guide contralateral targeting but not topographic mapping of ventral cochlear nucleus axons

Fig. 5

Topographic mapping is similar in wild type and ephrin-A2/A5 double knockout mice. a Scatter plot assessing topography using wild type mice (n = 16) shows a strong positive correlation between dye position in VCN and mean normalized position of contralateral calyces, with dorsal VCN regions projecting to medial MNTB, and ventral VCN projecting to lateral MNTB. b Analysis of topographic mapping in ephrin-A2/A5 double knockout mice (n = 7). The regression line and correlation coefficient is similar to results seen in wild type mice for projections to MNTBc as well as MNTBi. In these mice the ipsilateral calyces were significantly shifted laterally relative to the contralateral calyces

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