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Fig. 4 | Neural Development

Fig. 4

From: Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons

Fig. 4

Reduced Robo2 expression by Pax6 −/− thalamic neurons in chimeras. a,b Robo2 expression in wild-type thalamus at E16.5. c Diagram shows the positions of the thalamic areas photographed in d–i”; Th, thalamus; PTh, prethalamus. d–f Examples of the contributions of Pax6 −/− (GFP+) cells to the thalamus of three chimeras. g–i” Examples showing more intense staining for Robo2 mRNA (brown/purple) in WT cells than in clumps of GFP+ Pax6 −/− cells in the thalamus of a chimera aged E16.5. Scale bars: A,B, 100 μm; d–f, 75 μm; g–i”, 50 μm

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Neural Development

ISSN: 1749-8104