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Fig. 2 | Neural Development

Fig. 2

From: Developmental remodeling of relay cells in the dorsal lateral geniculate nucleus in the absence of retinal input

Fig. 2

Absence of retinal projections in SCN and dLGN of math5 −/−. Anterograde labeling of retinal projections with CTB in the SCN and dLGN of WT (a, d) and math5 −/− (b, e) adult mice. Retinal projections are visualized by injecting CTB conjugated to Alexa 488 (green; contralateral projections) in one eye and Alexa 594 (red; ipsilateral projections) in the other eye. Shown are coronal sections depicting SCN and dLGN for WT (a, d) and math5 −/− (b, e). Inverted grey scale images in B and E depict the complete absence of CTB labeling in math5 −/−. (c, f) Corresponding DAPI images for sections (b) and (e). Dashed lines outline the boundaries of dLGN and SCN, and scale bar = 200 μm

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