Skip to main content
Fig. 11 | Neural Development

Fig. 11

From: Netrin-1 directs dendritic growth and connectivity of vertebrate central neurons in vivo

Fig. 11

Perturbations in tectal netrin levels or signaling alter dendritic arbor directionality. a Proportion of neurons that developed ectopic basal projections within the 24-h period in each group. b Angle analysis performed on tectal neuron arbors sums all branch points to produce a net vector. The angle change was calculated from the tangents of arbors from 0 to 4 h. c The change in dendritic arbor directionality is shown as the difference in angle for neurons from 0 to 4 h and was measured both including (with) and excluding (without) ectopic projections. d Proportion of stable branches with net angle change. The percentage of stable branches that individually changed their angle by at least 10° was calculated for a subset of randomly selected neurons (n = 4). The individual branch tip vectors for each branch were compared from 0 to 4 h to calculate the angle change. Note that a larger proportion of stable branches altered their angle in neurons following anti-DCC treatment when compared to all other groups. Statistical significance was by Kruskal-Wallis Friedman with Dunn’s multiple comparison test. Significance when compared to control is *p < 0.05, **p < 0.01, ***p < 0.001. Error bars indicate SEM

Back to article page