Figure 10

Altered cell type distribution of Yfp ⁺ cells in regions of high Vsx2 ^orJ contribution in chimeras. Expression of POU4F (A) and OTX (B) in retinas of mutant chimeras at E15.5. Quantification of POU4F+ (C) and OTX+ (D) Yfp ⁺ cells as a function of patch type in retinas of mutant chimeras at E15.5. Black diamonds represent individual patch values and illustrate the variation within patches of the same type. Red squares represent mean ± standard deviation. P values calculated by Student’s unpaired t-test or Welch’s two-sample t-test, as appropriate (based on results of an F-test of variances). Scale bars: 100 μm. Abbreviations: EYFP, enhanced yellow fluorescent protein.