From: Dynamic regulation of mRNA decay during neural development
Neural-specific measurements: low-stability mRNAs | |||||
---|---|---|---|---|---|
GO term | Definition | P value | FDR | Count | Fold enrichment |
0006351 | Transcription | 4 × 10−10 | 2 × 10−7 | 58 | 2.5 |
 | svp, dpn, pros, vvl, grh, gsb, onecut |  |  |  |  |
0030182 | Neuron differentiation | 2 × 10−7 | 4 × 10−5 | 48 | 2.3 |
 | chinmo, Dl, tup, Ephrin, Eph, fax, shot |  |  |  |  |
0007067 | Mitosis | 6 × 10−5 | 3 × 10−3 | 21 | 2.9 |
 | cycB3, cdc27, Sse, cnn, glu, mts |  |  |  |  |
0018024 | Histone methyltransferase activity | 2 × 10−4 | .02 | 7 | 6.9 |
 | G9a, Set1, Set2, Su(z)12, ash1, egg |  |  |  |  |
0006897 | Endocytosis | 4 × 10−3 | .08 | 25 | 1.9 |
 | Arpc4, shi, CalpA, pat1, faf, scb, Rac1 |  |  |  |  |
0005840 | Ribosome | 2 × 10−3 | .06 | 21 | 2.0 |
 | RpL17, RpL35, mRpL11, mRpS35 |  |  |  |  |
Neural-specific measurements: high-stability mRNAs | |||||
GO term | Definition | P value | FDR | Count | Fold enrichment |
0048812 | Neuron projection morphogenesis | 5 × 10−6 | 6 × 10−4 | 33 | 2.4 |
 | trc, fusl, Fas2, Appl, Fmr1, otk, ben |  |  |  |  |
0003924 | GTPase activity | 2 × 10−4 | .02 | 17 | 2.9 |
 | Rab23, Rab30, Rab11, Rho1, Ras64B |  |  |  |  |
0012501 | Programmed cell death | 2 × 10−3 | .06 | 17 | 2.4 |
 | grim, pten, scyl, egr, mod(mdg4) |  |  |  |  |
0004672 | Protein kinase activity | 9 × 10−3 | .24 | 23 | 1.8 |
 | CamKI, Cdk4, Ror, ald, aur, nmo, trbl |  |  |  |  |
0019226 | Transmission of nerve impulse | .02 | .25 | 17 | 1.8 |
 | CASK, CanB, Dap160, cpx, Sap47 |  |  |  |  |
0051674 | Localization of cell | .01 | .16 | 18 | 1.9 |
 | cbl, APC, cortactin, par-6, baz, spri |  |  |  |  |