PREs increase the rate of transcript decay in the nervous system. (A) Reporter construct design. Hey WT 3’ UTR contains the single endogenous PRE. Hey PRE Δ 3’ UTR has only the PRE sequence removed. (B) Decay curves based on reverse-transcription, quantitative-PCR measurements of reporter transcript decay (using GFP primers). Chase times are plotted on the x-axis (0-hour = end of 1-hour pulse). Mean chase/pulse values at the 1-hour chase and 3-hour chase time points are plotted based on multiple measurements. Half-lives in minutes are listed next to the decay curve for each transcript.