Comparison of neural-specific and whole embryo decay measurements suggests many transcripts have neural-specific half-lives. (A) Distribution of mRNA half-lives in the whole embryo and neural-specific datasets. Only mRNAs with reproducible half-life measurements across replicates were included in the distribution and mean/median calculations. (B) Comparison of individual mRNA half-lives obtained by neural-specific versus whole embryo measurements. Spots represent the mean half-life of individual transcripts. Additional mRNAs with whole embryo half-lives estimated at ≥600 min are listed in Additional file 7. Select mRNAs with half-life differences of ≥1.5-fold are labeled, with statistical significance indicated by the FDR color code.