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Table 1 Confocal analysis of Fgf lineage cells at E18.5 and P40

From: Fgf signaling controls the telencephalic distribution of Fgf-expressing progenitors generated in the rostral patterning center

   

Fgf8 CreER/+

Fgf17 CreER/+

Structure

Age

Marker

Double positive/βgal +

Double positive/marker +

n

Double positive/βgal +

Double positive/marker +

n

Cortex

P40

PV (medial)

2%

10%

2

0%

0%

2

P40

PV (lateral)

4%

12%

2

3%

1%

2

P40

SS (medial)

2%

6%

2

0%

0%

2

P40

SS (lateral)

6%

17%

2

0%

0%

2

Septum

E18.5

Calbindin

2%

60%

1

17%

23%

1

E18.5

Calretinin

16%

58%

1

24%

19%

1

E18.5

Ctip2

24%

69%

1

15%

9%

1

E18.5

Nkx2.1

5%

74%

1

19%

20%

1

P40

ChAT (MS)

8%

77%

2

17%

33%

4

Diagonal band of Broca

E18.5

Calbindin

10%

50%

1

6%

19%

1

E18.5

Nkx2.1

2%

33%

1

9%

26%

1

E18.5

Tbr1

34%

95%

1

59%

41%

1

P40

ChAT

13%

80%

2

28%

44%

4

Striatum

P40

ChAT

23%

66%

3

64%

16%

3

P40

Ctip2

70%

9%

3

nd

nd

nd

P40

PV

1%

14%

2

0%

0%

2

P40

SS

2%

29%

2

nd

nd

nd

Globus pallidus

E18.5

Ctip2

96%

35%

1

71%

3%

1

E18.5

Nkx2.1

92%

37%

1

89%

4%

1

P40

Npas1

72%

28%

3

88%

5%

2

P40

PV

46%

38%

2

0%

0%

2

Nucleus basalis of Meynert

P40

ChAT

49%

75%

3

92%

43%

3

Ventral pallidum

P40

ChAT

42%

76%

3

95%

45%

3

  1. Quantification of confocal studies examining co-localization of βgal with cell type-specific markers in Fgf8 CreER/+; TauR and Fgf17 CreER/+; TauR animals (Tm E8.5). Parenthetical descriptors (lateral, medial, MS) indicate regional location within the structure. See also Additional file 4: Figures S4 and Additional file 5: Figure S5. Cortical interneuron counts are overestimates, as quantification was done only in regions containing βgal+ cells.