Figure 2

Distribution of Fgf lineage cells at E12.5. Comparison of Fgf (ISH), Cre (ISH), and βgal (Xgal stain) expression in E12.5 rostral (A-D,A′-D′,A″-D″) and caudal (E-H,E′-H′,E″-H″) coronal sections through the telencephalons of ROSA26R embryos (Tm E8.5). Note that there are Xgal⁺ cells rostral to the Fgf expression domains (we do not see Fgf8 or Fgf17 expression but we do see Xgal labeling in A-D″), and that in more caudal sections, Xgal⁺ cells are observed outside the Fgf expression domains (E-H″). Abbreviations: ob, olfactory bulb neuroepithelium; h, hippocampus; mge, medial ganglionic eminence; pfc, prefrontal cortex; s, septum. See also Additional file 2: Figure S2.