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Figure 6 | Neural Development

Figure 6

From: Polycomb group genes are required to maintain a binary fate choice in the Drosophila eye

Figure 6

Model for the regulation of Sens by Sce, Scm, and Pc in R7s. N is transiently activated in precursors that occupy the R7 niche. As a consequence, these precursors do not express Svp and will adopt one of the “inner” photoreceptor fates, R8 or R7. Transient N also represses Sens, preventing the precursors from becoming R8s and causing them instead to become R7s. These R7s remain prone to expressing Sens stochastically and, independently of N, use Sce, Scm, and Pc to ensure that Sens remains permanently off.

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