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Table 1 Distinctions between the two optic cup (OC)-specific Cre lines used in this study

From: Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling

CRE line

Onset

Expression pattern

Applications in this study

αP0 CREiresGFP

E10.5

Prospective CE and NR (PeripheralHI - CentralLO)

Whole genome expression screen; Proliferation analysis

Chx10 CRE-GFP

E10.5

Prospective CE and NR (Mosaic)

Genetic epistasis (Cre expression is not affected by SOX2 or β-Catenin)

  1. Abbreviations: CE ciliary epithelium, NE neural retina.
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Neural Development

ISSN: 1749-8104