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Figure 8 | Neural Development

Figure 8

From: Dynamic mechanisms of neuroligin-dependent presynaptic terminal assembly in living cortical neurons

Figure 8

Model of synaptic vesicle protein transport vesicle (STV) recruitment to a developing presynaptic terminal. (1) Axo-dendritic contact induces diffuse neurexin recruitment to the contact site. (2) STVs are not attracted to this site (bottom). Instead, they are trapped as they encounter this site during normal axonal transport (top). (3) As STVs become trapped, neurexin simultaneously clusters, resulting in the formation of a stable site of synaptic protein accumulation.

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