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Table 4 Manual search for genes associated with axonal regeneration processes show that they are differentially expressed in regenerative and non-regenerative stages

From: Genome-wide expression profile of the response to spinal cord injury in Xenopus laevis reveals extensive differences between regenerative and non-regenerative stages

Category

GenBank ID

Gene name

UniGene cluster description

log2FC

    

R1

R2

R6

NR1

NR2

NR6

Axonal guidance

BC108561

ngfr

Nerve growth factor receptor

0.21

-0.20

-0.31

-0.16

-0.05

1.20

 

X91191

epha4-a

EPH receptor A4

-0.25

-0.09

0.25

-0.42

-0.48

-1.36

 

BC043626

epha4-b

EPH receptor A4

-0.17

0.13

0.52

-0.51

-0.16

-1.28

 

BC060745

epha2

EPH receptor A2

-0.42

0.01

-0.01

0.07

1.01

1.46

 

BC077964

sema4b

Sema domain, immunoglobulin domain (Ig), transmembrane domain and short cytoplasmic domain, (semaphorin) 4B

-0.35

-0.01

0.19

0.08

0.43

-1.00

 

BC124869

sema3f

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3 F

0.19

0.30

0.18

0.29

1.15

1.64

 

AF427525

reln

Reelin

-0.30

0.21

0.32

-0.52

0.26

-1.16

Intrinsic factors

AY116304

klf15

Krüppel-like factor 15

-1.49

-0.58

-0.43

-0.46

0.64

-0.84

 

BC092147

klf10

Krüppel-like factor 10

-0.18

-0.10

-0.05

0.28

0.74

1.72

 

BC054214

socs3

Suppressor of cytokine signaling 3

2.12

2.00

1.72

2.15

3.72

4.62

 

BC068752

socs3

Suppressor of cytokine signaling 3

3.31

2.05

1.01

3.40

4.45

6.55

 

BC044717

stat3.2

Signal transducer and activator of transcription 3 (acute-phase response factor), gene 2

0.74

0.61

0.19

0.55

0.98

2.10

 

BC086272

stat6

Signal transducer and activator of transcription 6, interleukin-4 induced

-0.43

0.72

0.47

0.38

0.57

1.62

  1. Two categories are shown: genes related to axonal guidance and genes associated with intrinsic factors involved in axonal regeneration. FC, fold change (transected/sham).