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Table 3 Top 10 differentially regulated genes 6 days post transection

From: Genome-wide expression profile of the response to spinal cord injury in Xenopus laevis reveals extensive differences between regenerative and non-regenerative stages

GenBank ID

Gene name

UniGene cluster description

log2FC

FC ratio

 

R6

NR6

BC041209

rrm2b

Ribonucleotide reductase M2 B (TP53 inducible)

-0.29

5.76

66.26

X82012

kif4a

Kinesin family member 4A

-0.24

5.68

60.55

BC043778

kpna2

Karyopherin alpha 2 (RAG cohort 1, importin alpha 1)

-0.40

4.75

35.51

BC060435

MGC68771

Hypothetical protein MGC68771

1.02

6.08

33.36

BC070640

MGC81499

Hypothetical protein MGC81499

-0.41

4.58

31.78

AJ557446

kpna2

Karyopherin alpha-2 subunit like

-0.37

4.35

26.35

BC084431

kifc1

Kinesin family member C1

-0.18

4.39

23.75

BC154984

ctsk

Cathepsin K

0.69

5.17

22.32

BC099253

LOC446922

Hypothetical protein LOC446922

-0.84

3.58

21.41

BC044051

mcm3

MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)

-0.23

4.18

21.26

  1. Top 10 transcripts that, in addition to being differentially expressed after injury, show a different response when comparing regenerative and non-regenerative stages. Selection criteria: P < 0.01; sum of reads (transected + sham) higher or equal to the mean value of all transcripts. FC ratio: ratio between FC(R)/FC(NR) or FC(NR)/FC(R) (see Figure 2b for selection criteria). FC, fold change (transected/sham).