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Table 3 Top 10 differentially regulated genes 6 days post transection

From: Genome-wide expression profile of the response to spinal cord injury in Xenopus laevis reveals extensive differences between regenerative and non-regenerative stages

GenBank ID Gene name UniGene cluster description log2FC FC ratio
  R6 NR6
BC041209 rrm2b Ribonucleotide reductase M2 B (TP53 inducible) -0.29 5.76 66.26
X82012 kif4a Kinesin family member 4A -0.24 5.68 60.55
BC043778 kpna2 Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -0.40 4.75 35.51
BC060435 MGC68771 Hypothetical protein MGC68771 1.02 6.08 33.36
BC070640 MGC81499 Hypothetical protein MGC81499 -0.41 4.58 31.78
AJ557446 kpna2 Karyopherin alpha-2 subunit like -0.37 4.35 26.35
BC084431 kifc1 Kinesin family member C1 -0.18 4.39 23.75
BC154984 ctsk Cathepsin K 0.69 5.17 22.32
BC099253 LOC446922 Hypothetical protein LOC446922 -0.84 3.58 21.41
BC044051 mcm3 MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) -0.23 4.18 21.26
  1. Top 10 transcripts that, in addition to being differentially expressed after injury, show a different response when comparing regenerative and non-regenerative stages. Selection criteria: P < 0.01; sum of reads (transected + sham) higher or equal to the mean value of all transcripts. FC ratio: ratio between FC(R)/FC(NR) or FC(NR)/FC(R) (see Figure 2b for selection criteria). FC, fold change (transected/sham).