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Figure 5 | Neural Development

Figure 5

From: Caenorhabditis elegans Muscleblind homolog mbl-1 functions in neurons to regulate synapse formation

Figure 5

Localization of post-synaptic receptor ACR-16 and body wall muscle morphology is normal in mbl-1 . (A-F) Postsynaptic receptor ACR-16::GFP co-localizes with presynaptic mCherry::RAB-3 in wild type (A-C) and mbl-1(tm1563) (D-F) mutants in the dorsal nerve cord. ACR-16 is shown in green and RAB-3 is shown in red. (G, H) Dorsal body wall muscles labeled with myr-mCherry extend muscle arms towards the dorsal nerve cord where DA9 synapses are labeled with SNB-1::YFP. Muscles and SNB-1 are pseudocolored green and red, respectively. Two representative muscle arms are indicated with a white triangle for each genotype. (I, J) Lateral body wall muscles labeled with membrane-tethered yellow fluorescent protein (YFP; green) extend muscle arms towards the dorsal nerve cord labeled with mCherry (red). Four muscle arms, each indicated by a white triangle, are observed per muscle for both wild type and mbl-1(tm1563).

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