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Figure 5 | Neural Development

Figure 5

From: Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina

Figure 5

Mdka gain-of-function accelerates the cell cycle. (A) Representative raw data from FACS sorting of neural progenitors at 30 hpf. (B) Histograms showing the average percentage of cells in the G1-, S-, and G2-/M- phases of the cell cycle. *P <0.01. n=4 independent assays from a minimum of 5,000 cells/assay. (C) Graph showing the percent labeled mitoses for embryos between 28 hpf and 34 hpf. #*P <0.01. n=4 embryos/condition/time point. MO, embryos injected with mdka-targeted morpholinos; Tg, homozygous transgenic siblings treated with heat shock at 24 hpf; WT, untreated wild-type embryos.

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