Skip to main content
Figure 3 | Neural Development

Figure 3

From: Neurog1 and Neurog2 coordinately regulate development of the olfactory system

Figure 3

Impaired lamination and differentiation of excitatory neurons in Neurog1/2−/−single and double mutant olfactory bulbs. (A) to (X) Expression of NeuroD6 (A) to (D), Tcfap2e (E) to (H), Tbr1 (I) to (L), Tbr2 (M) to (P), vGlut1 (green)/DAPI (blue) (Q) to (T) and vGlut2 (green)/DAPI (blue) (U) to (X) in embryonic day 18.5 wild-type (A,E,I,M,Q,U), Neurog1−/− (B,F,J,N,R,V), Neurog2KI/KI (C,G,K,O,S,W) and Neurog1/2−/− (D,H,L,P,T,X) olfactory bulbs (OBs). White arrowheads in R,V,T,X mark diminished vGlut1/2 protein expression in the peripheral glomerular layer (GL). AON, anterior olfactory nucleus; MCL, mitral cell layer; OBLS, olfactory bulb-like structure; VZ, ventricular zone. Scale bars: 1 mm (A) to (D), 500 μm (E) to (X).

Back to article page