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Figure 4 | Neural Development

Figure 4

From: Olfactory discrimination largely persists in mice with defects in odorant receptor expression and axon guidance

Figure 4

mOR256-17 Immunocytochemical analysis of the adult olfactory bulb. In WT mice antibodies to the mOR256-17 OR identify two lateral glomeruli (arrows in A) and two medial glomeruli in the extreme caudal OB (arrows in B). In β3GnT2−/− mice there are four lateral glomeruli. The most rostral mutant glomerulus (arrow in C) is found in its approximate normal position compared to controls. Three additional lateral glomeruli in the null OB are located in an aberrant caudal and ventral position (arrows in D, E and F) compared to WT glomeruli. In β3GnT2−/− mice, there are three diffuse medial glomeruli, one of which (arrow in G) is in the approximate correct position. The other three medial glomeruli in the null OB are in either more ventral or more dorsal positions (arrows in G and H) compared to control glomeruli. Scale bar = 500 μM.

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Neural Development

ISSN: 1749-8104