Figure 5From: The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targetingOther BRM complex component mutants do not exhibit the same phenotypes as Bap55 mutants. (A) Dendrites of brm-/-DL1 PNs mistarget to non-stereotyped areas of the antennal lobe. (B, C) brm-/-anterodorsal (B) and lateral (C) neuroblast clone PNs exhibit perturbed cell morphology, weak labeling, and dendrite mistargeting, with small meandering projections to incorrect glomeruli. (D) brm-/-ventral neuroblast clone PNs exhibit perturbed cell morphology, weak labeling, and a lack of innervation throughout the antennal lobe. (E) Dendrites of Snr1-/-DL1 PNs mistarget to non-stereotyped areas of the antennal lobe. (F, G) Snr1-/-anterodorsal (F) and lateral (G) neuroblast clone PNs exhibit perturbed cell morphology, weak labeling, and dendrite mistargeting, with small meandering projections to incorrect glomeruli. (H) Snr1-/-ventral neuroblast clone PNs exhibit perturbed cell morphology, weak labeling, and a lack of innervation throughout the antennal lobe. Green marks mCD8-GFP-labeled PNs generated by MARCM and labeled using GH146-GAL4. All panels show full confocal stacks; magenta is the presynaptic marker nc82; symbols are as in Figure 2. Scale bar: 20 μm in (A) (for A-H).Back to article page