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Figure 3 | Neural Development

Figure 3

From: The BTB/POZ zinc finger protein Broad-Z3 promotes dendritic outgrowth during metamorphic remodeling of the peripheral stretch receptor dbd

Figure 3

Outgrowth of dbd dendrites. Z-projections from two-photon time-lapse videos showing dbd (arrowhead) and neuron ddaE (e) between 28 h and 40 h APF. (A) Control migrating dbd (arrowheads) extended a large growth cone (arrow) along the nerve, passed ddaE (e), ceased migration, then began posterior outgrowth by 40 h APF. (B) In neurons expressing BrZ3 (dbd[+BrZ3]), outgrowth began before migration was complete (arrows). (C) Time of initiation of dendrite outgrowth, using the metric of reaching twice the length of the growth cone. Control, 36.6 ± 1.8 h APF (mean ± standard error of the mean), n = 4; dbd[+BrZ3], 29.4 ± 0.9 h APF, n = 9; *P = 0.0017. Scale bar = 30 μm.

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Neural Development

ISSN: 1749-8104