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Figure 8 | Neural Development

Figure 8

From: Basal progenitor cells in the embryonic mouse thalamus - their molecular characterization and the role of neurogenins and Pax6

Figure 8

Co-expression of various transcription factors with postmitotic neuronal markers. Confocal images of E11.5 frontal sections showing double staining of various transcription factors and NeuN (A-E) or the cyclin-dependent kinase inhibitor p27 (F-J). Midline is to the left. (A-D) Neurog1, Neurog2, NeuroD1 and Olig2 show almost no overlap with the postmitotic neuronal maker NeuN. NeuN-expressing cells are restricted to the lateral part of the section. (E) Lhx2/9 and NeuN are co-expressed. (F-I) Neurog1, Neurog2, NeuroD1 and Olig2 show some co-expression with the cyclin-dependent kinase inhibitor p27 in the VZ and SVZ (arrowheads). (J) Abundant co-localization of Lhx2/9 and p27 in both the VZ/SVZ (arrowheads) and the mantle zone. Scale bar: 50 μm.

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