Figure 6

Mitosis is not significantly affected in the Loa/Loa brains. (A) Wild-type and Loa/Loa brain sections immunostained with PH3, which is expressed during mitosis. There was no significant difference in the location of mitotic cells (either in ventricular or abventricular regions), or in the number of mitotic cells between the two genotypes, as depicted in the corresponding graphs (average number of cells ± standard deviation). Scale bar = 100 μm. (B) BrdU pulse-labeling of wild-type and Loa/Loa embryos reveals no significant difference between the number of BrdU-labeled cells as shown in the images and graph (average number of cells ± standard deviation). Scale bar = 100 μm.