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Figure 3 | Neural Development

Figure 3

From: EphA4 expression promotes network activity and spine maturation in cortical neuronal cultures

Figure 3

Mean values for burst duration and spikes per burst at 7 and 14 DIV. (A) Average burst duration in control (C, white) and EphA4-transfected (A4, black) primary cortical networks at 7 DIV (left) and 14 DIV (right). EphA4 transfected networks have significantly longer bursts than control networks at both time points. (B) Average number of spikes per burst in control (white) and EphA4-transfected (black) networks at 7 DIV (left) and 14 DIV (right). Bursts from EphA4-transfected networks contain significantly more spikes than control networks at 14 DIV, but not 7 DIV. Bursts at 14 DIV are significantly longer and have more spikes than bursts at 7 DIV in both groups. (***P < 0.0001 as determined using ANOVA, error bars represent the standard error of the mean).

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