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Figure 5 | Neural Development

Figure 5

From: Bazooka mediates secondary axon morphology in Drosophila brain lineages

Figure 5

BAla1 clones lacking Bazooka retain dendrite and axon morphology. (A) Ventral projection neuron (vPN) terminal branches retained bulbous morphology in an adult preparation of a baz loss-of-function (LOF) BAla1 clone. (B) vPN proximal branches in the glomeruli of the antennal lobe exhibited typical postsynaptic spiny morphology. (C,E,G) The typical pattern of glomeruli infiltration by the proximal branches of the ventral projection neurons was retained in (D,F,H) clones containing the baz4 null allele. The glomeruli innervated are indicated to the left of each row. (I) Terminal branching of a control BAla1 clone into the lateral horn. Note all branching stems from a single fascicle (arrow) and branching reached into both the dorsal (double arrowhead) and ventral (arrowhead) lateral horn. (J) Terminal branching of a baz LOF BAla1 clone into the lateral horn. Note that branching stemmed from both a ventral fascicle (arrow) and a set of dorsal fasicles (double arrows), and that the lateral horn area innervated correlated with the point of fascicle entry (dorsal innervation with dorsal entry, double arrowhead; ventral innervation with ventral entry, arrowhead). The neuropile was labeled with anti-Drosophila N-cadherin in all panels (magenta). Scale bars: 10 μm

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