Figure 2
From: Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells
Neurog2 progeny populate distinct OB layers during embryonic development. (A,C,E) Overview of the distribution of GFP-positive cells in the OB of P21 Neurog2CreERT2 × TaukiGFP mice. The recombination was induced at E13.5 (A), E17.5 (C) and at birth (E) by a single injection of tamoxifen. DAPI counterstaining (blue) on the left side of the photomicrograph visualizes the distinct OB layers. (B,D,F) Quantification of the percentage of Neurog2-derived GFP-positive cells observed in the OB layers following tamoxifen injection at E13.5 (B), E17.5 (D) and at birth (F). Scale bar: 100 μm. EPL, external plexiform layer; GL, glomerular layer; GCL, granular cell layer; MCL, mitral cell layer. Error bars indicate S.E.M.