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Figure 5 | Neural Development

Figure 5

From: The neuroepithelial basement membrane serves as a boundary and a substrate for neuron migration in the zebrafish hindbrain

Figure 5

aPKC functions cell non-autonomously to prevent ventral mismigration. Maximum intensity projections of 48-hpf embryos in which rhodamine-dextran-labeled, tg(isl1:GFP) donor cells were transplanted into tg(isl1:GFP) transgenic hosts. (A, B) Yellow colocalization indicates donor-derived FBMNs. Wild-type (WT) donor cells transplanted into WT hosts never mismigrate ventrally. (C, D) A subset of WT FBMNs transplanted into an aPKCλ+ζ morphant host mismigrates ventrally (arrow).

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Neural Development

ISSN: 1749-8104