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Figure 7 | Neural Development

Figure 7

From: Cortico-cerebral histogenesis in the opossum Monodelphis domestica: generation of a hexalaminar neocortex in the absence of a basal proliferative compartment

Figure 7

Distribution of GABA and glutamate-decarboxylase immunoreactivity in developing opossum cortices. (Aa-d) Distribution of GABA+ cells on frontal sections of P1 to P14 cortices. (Aa'-d') Magnifications of boxed regions in (Aa-d). (Ba-c) Distribution of glutamate-decarboxylase (GAD)+ cells on frontal sections of P4, P8 and P10 cortices. (Ba'-c') Magnifications of boxed regions in (Ba-c). GAD+ cells are evident in the marginal zone and the subplate since P4 (Ba',b', solid arrowheads). At P8, an additional reactivity is detectable in proliferative layers (Bb', empty arrowheads). Finally, at P10, both marginal zone and periventricular GAD signals are strengthened (Bc',c") and additional GAD+ cells are present throughout the cortical plate (Bc'). Abbreviations: cp, cortical plate; iz, intermediate zone; mz, marginal zone; sp, subplate; vz, ventricular zone. Scale bars: 400 μm in (Aa-d,Ba-c); 50 μm in (Aa'-d', Ba'-c").

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