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Table 2 Percentage of embryos (sides) examined with cranial nerve abnormalities

From: Nav2 is necessary for cranial nerve development and blood pressure regulation

Genotype

Phenotype 1: gIX weakly or not connected to hindbrain

Phenotype 2: CN IX/X fusion

Phenotypes 1 and 2 combined

Wild type

7% (4/59)

7% (4/59)

14% (8/59)

Homozygote

27% (72/266)

17% (45/266)

44% (117/266)

  1. Values shown in parentheses are the number of abnormal observations over the total number of observations (60 wild-type and 133 homozygous embryos were scored on both the right and left side; one wild-type side (observation) was lost). Phenotype 1: Z-score = -3.33 and P-value ≤ 0.001. Phenotype 2: Z-score = -1.97 and P-value ≤ 0.05. Phenotypes 1 and 2 combined: Z-score = -4.35; P-value ≤ 0.0001. gIX, ganglia IX.
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Neural Development

ISSN: 1749-8104