Figure 5
From: Nav2 is necessary for cranial nerve development and blood pressure regulation
Nav2 is expressed in the mesencephalic tract, cranial and dorsal root ganglia and neural tube at E10.5. (A-F) Nav2 mRNA expression in transverse vibratome sections of a wild-type embryo. Representative sections (200 μm) were analyzed by in situ hybridization using a riboprobe to Nav2. Staining for Nav2 is present in the mesencephalic tract (mes) neurons (A), trigeminal ganglia (V) (B), ganglia of VII and VIII (C), the ganglia of IX (D1) and X (E1) as well as the dorsal root ganglia (drg) (F). β-III tubulin antibody staining in vibratome sections (D2, E2) overlaps with that of the Nav2 riboprobe in the ganglia of cranial nerve IX (D1) and X (E1). The approximate location of the vibratome sections with respect to the whole embryo is shown by a dotted line in the illustration. e, eye; nt, neural tube; ov, otic vesicle. Scale bar: 200 μm.