Figure 8
From: Developmental control of lateralized neuron size in the nematode Caenorhabditis elegans
Model for size regulation in ASEL/R. die-1 gene activity controls left/right asymmetric functional features, such as asymmetric expression of the putative gcy chemoreceptors, and is required for the asymmetric size of ASEL versus ASER as well as the asymmetric number of FIB-1(+) nucleoli in ASEL versus ASER. The effect of die-1 on size cannot solely be explained through regulation of fib-1, as fib-1 is required but not sufficient to impose ASER size. die-1 may therefore regulate the expression of other genes involved in size control. die-1 may regulate fib-1 expression directly or indirectly (as indicated with the question mark).