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Figure 6 | Neural Development

Figure 6

From: Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum

Figure 6

Expression of tau protein in axon-like fibers of nascent Purkinje cells at E13.5. (A-G) Cerebellar sections were first treated with anti-Corl2 (magenta in (C-G); nuclear) and anti-tau (green in (C-G)), and then stained with anti-Nestin (magenta in (D, E); fibrous); (C, F, G) show images before anti-Nestin immunostaining and (D, E) show images after it. Panels (C-E) show magnified views as indicated in (A, B). Panel (E) was made by superimposing colored fluorescent images on black-and-white images to increase the visibility of the tissue structure. Intense tau immunoreactivity was detected in a thickened proximal part (arrowheads) of the axon-like radial or tangential processes. Note that the tau+ tangential fiber crosses the Nestin+ radial fiber (D, E).

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Neural Development

ISSN: 1749-8104