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Figure 12 | Neural Development

Figure 12

From: Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling

Figure 12

RA does not affect the proliferation of NPCs in culture. (A) NPCs grown as neurospheres were treated with various concentrations of RA (0, 10-9, 10-8 and 10-6 M) and after 3 DIV the number of BrdU-positive cells was analyzed. RA treatment did not have any effect on NPC proliferation at any of the concentrations studied. (B) The same result was observed when NPC cultures were treated with a RARβ-specific agonist (10-8 M). Values are normalized to control (not treated with RA or RARβ agonist), considered as 100%, and expressed as the mean ± standard error of the mean from at least three independent samples for each condition.

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