Figure 10
From: Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling
Gsx2 is a permissive factor for Nolz1 expression. (A-C) Nolz1 mRNA expression is detected in E14.5 wild-type mice (Gsx2+/+; A) and Gsx2+/EGFPmice (B), but totally disappears in the vLGE of Gsx2EGFP/EGFPmice (C). Scale bars: 600 μm. (D) Gsx2 over-expression in NPCs does not modify Nolz1 mRNA levels, although it increases Raldh3 mRNA expression. The results represent the mean ± standard error of the mean from at least three independent samples at each condition. Statistical analysis was performed with the Student's t-test. *P < 0.05, relative to control.