Figure 3

Acute effects of TNF-α application on voltage-gated currents and spontaneous synaptic transmission in tectal neurons. (A) I-V curves for Na⁺ and K⁺ currents in control tectal cells and cells acutely (approximately 1 h) treated with TNF-α. (B) Maximum peak amplitudes (pA) of Na⁺ and K⁺ currents from both groups show no significant differences. (C) Spontaneous EPSCs recorded from control neurons and neurons acutely (approximately 1 h) treated with TNF-α. (D) TNF-α-treated tadpoles exhibited a higher frequency of sEPSCs than controls but showed no difference in amplitude. Asterisk indicates p < 0.05, for actual P-values see Results.