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Table 1 Axon guidance phenotypes in Netrin-1 mutant mice

From: Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II

Axon guidance defect

Netrin-1 +/+

Netrin-1 +/-

Netrin-1 -/-

Early axon turning to exit point

0/5

3/14

9/10

Rhombomere 4 fascicles projecting longitudinally short distances in floor plate

0/5

1/14

4/10

Long axon fascicle in floor plate

0/5

4/14

5/10

  1. Data based on a combination of neurofilament immunostaining and DiI labelling.
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Neural Development

ISSN: 1749-8104