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Figure 6 | Neural Development

Figure 6

From: Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II

Figure 6

Blebbistatin causes a loss of correct motor axon pathfinding in explants. (A,B) Stage 17 to 18 chick hindbrain explants (r6/7 level) cultured in collagen gels with control medium (A) or blebbistatin (B) showing axon stalling and loss of projection from the midline. Scale bar = 100 μm. (C) Histogram representing mean percentage of explants showing different grades of axon pathfinding defects in controls or those treated with blebbistatin at 20 μM.

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