Figure 4
From: Assembly of the outer retina in the absence of GABA synthesis in horizontal cells
Horizontal cell and photoreceptor lamination are not grossly disrupted in the absence of GABA in the outer retina. (a) Horizontal cells from a P5 mutant retina immunolabeled for calbindin. In both littermate control and mutant retinas, the processes of these cells are stratified within the outer retina. (b) Photoreceptor terminals in a P5 mutant retina immunostained for vesicular glutamate transporter 1 (vGluT1). The terminals are stratified in both littermate control and mutant retinas. The slight irregularity of the mutant vGlut1 lamination is not unusual at this age and can be observed in the wild-type retina as well. hc, horizontal cells; ac, amacrine cells.