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Table 2 Ultrastructure morphometrics

From: Analysis of a zebrafish dync1h1mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development

 

Cell area

(average ± SEM)

OS morphology

Cellular phenotypes

Specimen

PhR area (μm2/cell)

OS area (μm2/cell)

Normal (% OS)

Vesiculated (% OS)

Polarized with OS (%)

Polarized no OS (%)

Depolarized cell (%)

Apoptotic nucleus (%)

Central

        

   Cntrl MO

22.0 ± 10.5

4.4 ± 0.3

89

11

64

36

0

0

   dync1MO

20.9 ± 9.6

3.3 ± 0.2*

70†

30†

30†

49†

17†

5†

   cnb

19.8 ± 13.2

3.5 ± 0.3*

86

14

16†

37†

32†

15†

Peripheral

        

   Cntrl MO

21.7 ± 14.6

4.0 ± 0.3

88

12

47

53

0

0.01

   dync1MO

19.9 ± 12.5

3.0 ± 0.5*

60†

40†

5†

47†

40†

9†

   cnb

20.0 ± 11.2

2.6 ± 0.6*

75†

25†

4†

14†

62†

20†

  1. *P < 0.05 versus control morpholino (Cntrl MO) in central or peripheral regions (Student's t-test).
  2. †P < 0.05 versus cntrl MO in central or peripheral regions (X2 test). OS, outer segment; PhR, photoreceptor; SEM, standard error of the mean.