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Figure 1 | Neural Development

Figure 1

From: Pharmacological manipulation of GABA-driven activity in ovo disrupts the development of dendritic morphology but not the maturation of spinal cord network activity

Figure 1

Network activity in the E8 and E10 chicken spinal cord. (A) Fluorescent image of a transverse spinal cord section showing the location of the recording electrode in the motoneuron pool as indicated by the location of the DiI fluorescent spot. (B) Typical trace obtained by recording spontaneous activity in an E10 spinal cord. (C) Expanded trace of spontaneous activity generated in an E10 chicken spinal cord. Each episode of activity consisted of a fast rising component that develops into a series of bursts (asterisks). (D) Spontaneous activity generated in an E8 chicken spinal cord. The bursts of activity within each episode at E8 (asterisks) are small and long lasting when compared with bursts generated at E10. Notice that the episode duration was shorter than that generated in E10 spinal cords and consisted of a few bursts (asterisk). (E, F) Comparison of episode duration (E) and inter-episode interval (F) in E8 and E10 chicken spinal cords. In (E, F), asterisks represent P < 0.05 versus E8.

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