Figure 4
From: The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis
xCdc4 is found in ectodermal and mesodermal derivatives. (A-L) xCdc4 ISH on transverse sections of stage 15, 18 and 22 embryos (A,B,G-I), including sense control (E,F,J-L) and comparative Snail2 expression on stage 15 (C) and stage 18 (D) embryo sections. xCdc4 expression is detected in the neural crest (NC, black arrows), preplacodal ectoderm (ppe) and neural plate border (NPB) as well as in the neural plate (np). In addition to the expression in both superficial and deep layers of the ectoderm, there is also expression of xCdc4 in the notochord (n) and in somitogenic mesoderm (sm).