Figure 6
From: Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice
The subcallosal sling fails to form correctly in Nfib knockout mice. (A-D) Coronal sections of E18 brains showing expression of Emx1 (A, B) and NFIA (C, D). In the wildtype, cells of the subcallosal sling were seen crossing the midline immediately ventral to the CC (arrows in (A, C)). In the mutant, however, cells of the sling did not cross the midline, and instead remained ipsilateral (arrowheads in (B, D)). Scale bar: 200 μm.