Figure 5
From: Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain
Extracellular and intracellular Wnt inhibitors - Sfrp1 , Sfrp2 , Sfrp3 , Axin1 , Axin2 and Idax. (A-O) Expression of Sfrp1 (A-C), Sfrp2 (D-F), Sfrp3 (G-I), Axin1 (J,M), Axin2 (K,L,N) and Idax (O) at HH13 (A,D,G,J), HH14 (K), HH15 (H), HH16 (B,E,L), HH19 (C) and HH20 (F,I,M-O). (J-O) Double stainings with Shh in red. Lateral views of whole mount (A,D,J-O) or hemisected brains (B,C,E-I) are shown; anterior points to the right. Asterisks mark the commissural plate in (A-C). Note the absence of Sfrp2 expression from a dorsal patch between the telencephalon and diencephalon at HH13 and HH16 (arrowheads, D,E). The arrowhead in (F) indicates Sfrp2 expression in the pallium-subpallium boundary. Note the strong expression of Sfrp3 in the ventral diencephalon/midbrain (arrowheads, G,H). Scale bars represent 0.2 mm.