Table 1 Microtubule polymerization rates in developing neurons and PC12 cells
Cell population | ANTEROGRADE EVENTS Mean Velocity (μm/sec ± SE) | RETROGRADE EVENTS Mean Velocity (μm/sec ± SE) | ||
|---|---|---|---|---|
Hippocampal neurons | Axons | Dendrites | Axons | Dendrites |
1–2 DIV | 0.23 ± 0.02 (142) | 0.25 ± 0.02 (114) | 0.29 ± 0.05 (22) | 0.20 ± 0.05 (9) |
3–4 DIV | 0.26 ± 0.01 (214) | 0.36 ± 0.02 (199) | 0.43 ± 0.20 (5) | 0.27 ± 0.03 (44) |
> 7 DIV | 0.33 ± 0.02 (86) | 0.22 ± 0.03 (68) | 0.35 (1) | 0.18 ± 0.03 (21) |
PC12 Cells | 0.18 ± 0.003 (382) | 0.17 ± 0.01 (86) | ||