Figure 7
From: Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells
Ccnd1 -deficiency causes alterations in the proportions of precursor cell populations. Expression patterns of (A, D, H, K, O, R) PTF1A, (B, C, I, L, P, S) BHLHB5 and (C, F, J, M, Q, T) OTX2 at E12 (A-F), E14.5 (H-M), and P0 (O-T) are shown. (G, N, U) Quantification of marker+ cells at E12 (G), E14.5 (N), and P0 (U). Abbreviations: DCL, differentiated cell layer; NBL, neuroblast layer; PR, peripheral retina; RPE, retinal pigmented epithelium. Scale bar: 100 μm; (F) is representative for (A-F); (M) for (H-M); (T) for (O-T).