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Figure 1 | Neural Development

Figure 1

From: Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells

Figure 1

Expression patterns of CCND1 and acTUBB3 during early retinal development. Wild-type retinas were double-labeled with antibodies against (A-D) CCND1 and (E-H) acTUBB3. (I-L) Merged images. Dashed lines indicate the peripheral extent of strong CCND1+ cells in retinas from E11 (B, F, J), E12 (C, G, K), and E14.5 (D, H, L) embryos. Asterisks in (A, E, I) indicate that this region of the neuroepithelium is folded over in the section. Abbreviations: D, diencephalon; DCL, differentiated cell layer; L, lens; NBL, neuroblast layer; NR, neural retina; OV, optic vesicle; PNR, presumptive neural retina; SE, surface ectoderm. Scale bars: 100 μm; (K) is representative for (A-C, E-G, I-K); (L) is representative for (D, H, L).

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