Figure 2
From: Xenopus NM23-X4 regulates retinal gliogenesis through interaction with p27Xic1
Interaction between NM23 and CDKIs. (A) Co-immunoprecipitation of NM23-X4 and p27Xic1 in COS7 cells. p27Xic1 interacts strongly with NM23-X4 in the presence of the proteasome inhibitor MG132. (B) Interaction of p27Xic1 with NM23-X1, -X2, -X3, -X4, -X5, or -X6. (C) Interaction of p27Xic1 with the human NM23-H1 and -H4 homologs. (D) NM23-X4 interacts strongly with human p21Cip1 and p57Kip2, but not with p27Kip1. All analyses were performed in COS7 cells in the presence of MG132 unless otherwise stated.